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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620944
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp7
Name: caspase 7
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp7multiple interactionsEXP 6480464CTD[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]PMID:22085843
Casp7multiple interactionsISOCASP7 (Homo sapiens)6480464CTD[Chelating Agents binds to Copper] which results in increased expression of CASP7 mRNA; [NSC 689534 binds to Copper] which results in increased activity of CASP7 proteinPMID:20971185 PMID:30911355
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