GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pik3c3 | multiple interactions | ISO | PIK3C3 (Homo sapiens) | 6480464 | CTD | 3-methyladenine inhibits the reaction [Hydrogen Peroxide promotes the reaction [BECN1 protein binds to PIK3C3 protein]]; [3-methyladenine results in decreased activity of PIK3C3 protein] which results in decreased susceptibility to Hydrogen Peroxide; Hydrogen Peroxide promotes the reaction [BECN1 protein binds to PIK3C3 protein]; PIK3C3 protein promotes the reaction [Hydrogen Peroxide results in increased activity of BAX protein] | PMID:20525898 PMID:21742779 | Pik3c3 | multiple interactions | ISO | Pik3c3 (Mus musculus) | 6480464 | CTD | [Hydrogen Peroxide co-treated with procyanidin B2] results in increased expression of PIK3C3 mRNA | PMID:27057282 | |
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