GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dusp5 | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of DUSP5 mRNA | PMID:33387578 | Dusp5 | decreases expression | ISO | DUSP5 (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of DUSP5 mRNA | PMID:12377990 PMID:19619570 PMID:20106945 PMID:21632981 | Dusp5 | decreases expression | ISO | Dusp5 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of DUSP5 mRNA | PMID:19933214 | Dusp5 | multiple interactions | ISO | DUSP5 (Homo sapiens) | 6480464 | CTD | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of DUSP5 mRNA; [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNA; [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 protein; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 protein] | PMID:19578757 PMID:19619570 | |
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