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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620854
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dusp5
Name: dual specificity phosphatase 5
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dusp5increases expressionISODUSP5 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of DUSP5 mRNAPMID:25596134
Dusp5multiple interactionsISODUSP5 (Homo sapiens)6480464CTD[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNA; [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 protein; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNA]; alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 protein]PMID:19578757
Dusp5multiple interactionsISODusp5 (Mus musculus)6480464CTD[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of DUSP5 protein; epigallocatechin gallate inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of DUSP5 protein]PMID:34740634
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