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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620817
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aifm1
Name: apoptosis inducing factor, mitochondria associated 1
Acc ID: CHEBI:52722
Term: lactacystin
Definition: L-Cysteine substituted at nitrogen by an acetyl group and at sulfur by a substituted-lactam carbonyl group.
Chemical ID: MESH:C067713
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aifm1affects localizationISOAifm1 (Mus musculus)6480464CTDlactacystin affects the localization of AIFM1 proteinPMID:16860906
Aifm1increases localizationISOAifm1 (Mus musculus)6480464CTDlactacystin results in increased localization of AIFM1 proteinPMID:21683092
Aifm1multiple interactionsISOAifm1 (Mus musculus)6480464CTDATRN protein affects the reaction [lactacystin affects the localization of AIFM1 protein]; U 0126 inhibits the reaction [lactacystin results in increased localization of AIFM1 protein]PMID:16860906 PMID:21683092
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