GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hes1 | increases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in increased expression of HES1 mRNA; Benzo(a)pyrene results in increased expression of HES1 protein | PMID:35378083 | Hes1 | multiple interactions | EXP | | 6480464 | CTD | Benzo(a)pyrene promotes the reaction [Dibutyl Phthalate results in increased expression of HES1 mRNA]; Benzo(a)pyrene promotes the reaction [Dibutyl Phthalate results in increased expression of HES1 protein]; Dibutyl Phthalate promotes the reaction [Benzo(a)pyrene results in increased expression of HES1 mRNA]; Dibutyl Phthalate promotes the reaction [Benzo(a)pyrene results in increased expression of HES1 protein] | PMID:35378083 | Hes1 | decreases methylation | ISO | HES1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of HES1 3' UTR | PMID:27901495 | Hes1 | increases expression | ISO | HES1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of HES1 mRNA | PMID:20064835 PMID:20106945 PMID:21871943 PMID:22316170 PMID:26238291 | |
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