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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620795
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Src
Name: SRC proto-oncogene, non-receptor tyrosine kinase
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srcmultiple interactionsEXP 6480464CTD[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of SRC protein; Antigen-Antibody Complex inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of SRC protein]; Chlorpromazine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of SRC protein]PMID:29702141
Srcdecreases expressionISOSrc (Mus musculus)6480464CTDGlucose results in decreased expression of SRC proteinPMID:31483951
Srcmultiple interactionsISOSrc (Mus musculus)6480464CTD[Resveratrol co-treated with Glucose] results in decreased expression of SRC mRNA; [Resveratrol co-treated with Glucose] results in decreased expression of SRC protein; [Resveratrol co-treated with Glucose] results in decreased expression of SRC protein modified form; Eucalyptol inhibits the reaction [Glucose results in decreased expression of SRC protein]; SRC protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]PMID:11990355 PMID:24659233 PMID:31483951
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