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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620770
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gnaq
Name: G protein subunit alpha q
Acc ID: CHEBI:37550
Term: sphingosine 1-phosphate
Definition: A phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1
Chemical ID: MESH:C060506
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnaqincreases expressionISOGNAQ (Homo sapiens)6480464CTDsphingosine 1-phosphate results in increased expression of GNAQ proteinPMID:25980589
Gnaqmultiple interactionsISOGNAQ (Homo sapiens)6480464CTDFingolimod Hydrochloride inhibits the reaction [sphingosine 1-phosphate results in increased expression of GNAQ protein]; Phytochemicals analog inhibits the reaction [sphingosine 1-phosphate results in increased expression of GNAQ protein]PMID:25980589
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