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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62071
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gap43
Name: growth associated protein 43
Acc ID: CHEBI:30802
Term: isophthalic acid
Definition: A benzenedicarboxylic acid that is benzene substituted by carboxy groups at position 1 and 3. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and terephthalic acids.
Chemical ID: MESH:C059768
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gap43increases expressionISOGAP43 (Homo sapiens)6480464CTDisophthalate analog results in increased expression of GAP43 mRNA; isophthalate analog results in increased expression of GAP43 proteinPMID:23643828
Gap43multiple interactionsISOGAP43 (Homo sapiens)6480464CTDGo 6976 inhibits the reaction [isophthalate analog results in increased expression of GAP43 protein]PMID:23643828
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