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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620683
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rps6kb1
Name: ribosomal protein S6 kinase B1
Acc ID: CHEBI:48958
Term: 1,1'-azobis(N,N-dimethylformamide)
Definition: A monoazo compound that has formula C6H12N4O2.
Chemical ID: MESH:D003958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rps6kb1increases phosphorylationISORPS6KB1 (Homo sapiens)6480464CTDDiamide results in increased phosphorylation of RPS6KB1 proteinPMID:16183647
Rps6kb1multiple interactionsISORPS6KB1 (Homo sapiens)6480464CTD[Diamide results in increased activity of MTOR protein] which results in increased phosphorylation of RPS6KB1 protein; MTOR mutant form inhibits the reaction [Diamide results in increased phosphorylation of RPS6KB1 protein]; RPTOR mutant form inhibits the reaction [Diamide results in increased phosphorylation of RPS6KB1 protein]PMID:16183647
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