GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rps6kb1 | increases phosphorylation | EXP | | 6480464 | CTD | arsenite results in increased phosphorylation of RPS6KB1 protein | PMID:17038550 PMID:20377179 | Rps6kb1 | multiple interactions | EXP | | 6480464 | CTD | Quercetin inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein] | PMID:20377179 | Rps6kb1 | decreases phosphorylation | ISO | Rps6kb1 (Mus musculus) | 6480464 | CTD | arsenite results in decreased phosphorylation of RPS6KB1 protein | PMID:20589738 | Rps6kb1 | increases phosphorylation | ISO | RPS6KB1 (Homo sapiens) | 6480464 | CTD | arsenite results in increased phosphorylation of RPS6KB1 protein | PMID:22215663 | Rps6kb1 | increases phosphorylation | ISO | Rps6kb1 (Mus musculus) | 6480464 | CTD | arsenite results in increased phosphorylation of RPS6KB1 protein | PMID:22215663 PMID:23396362 | Rps6kb1 | multiple interactions | ISO | RPS6KB1 (Homo sapiens) | 6480464 | CTD | 2-(methylamino)isobutyric acid inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein]; [sodium arsenite results in increased abundance of arsenite] which results in increased phosphorylation of RPS6KB1 protein; Sirolimus inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein]; SLC38A2 mutant form inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein] | PMID:22215663 PMID:31781319 | Rps6kb1 | multiple interactions | ISO | Rps6kb1 (Mus musculus) | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Egtazic Acid inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; NFKB1 protein affects the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein]; pyrazolanthrone inhibits the reaction [arsenite results in decreased phosphorylation of RPS6KB1 protein]; Sirolimus inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Sirolimus inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein]; Wortmannin inhibits the reaction [arsenite affects the activity of RPS6KB1 protein] | PMID:14516795 PMID:20589738 PMID:22215663 PMID:23396362 | |
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