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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620666
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map2k6
Name: mitogen-activated protein kinase kinase 6
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map2k6affects methylationEXP 6480464CTDDoxorubicin affects the methylation of MAP2K6 genePMID:28962528
Map2k6affects activityISOMAP2K6 (Homo sapiens)6480464CTDDoxorubicin affects the activity of MAP2K6 proteinPMID:15870702
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