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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620640
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2d4
Name: cytochrome P450, family 2, subfamily d, polypeptide 4
Acc ID: CHEBI:134938
Term: ozagrel
Definition: null
Chemical ID: MESH:C034364
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2d4increases metabolic processingEXP 6480464CTDCYP2D6 protein results in increased metabolism of ozagrelPMID:17651725
Cyp2d4multiple interactionsEXP 6480464CTDozagrel promotes the reaction [CYP2D6 protein results in increased metabolism of Dextromethorphan]; ozagrel results in increased expression of and results in increased activity of CYP2D6 proteinPMID:17651725
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