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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620525
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mcl1
Name: MCL1 apoptosis regulator, BCL2 family member
Acc ID: CHEBI:28584
Term: gossypol
Definition: A polyphenol that has formula C30H30O8.
Chemical ID: MESH:D006072
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mcl1decreases expressionISOMCL1 (Homo sapiens)6480464CTDGossypol results in decreased expression of MCL1 proteinPMID:18840529 PMID:20587533 PMID:21750559
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