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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620486
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Erbb4
Name: erb-b2 receptor tyrosine kinase 4
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Erbb4multiple interactionsISOErbb4 (Mus musculus)6480464CTD[Lipopolysaccharides co-treated with ERBB4] affects the expression of TNF protein; ERBB4 protein affects the reaction [Lipopolysaccharides results in decreased expression of SFTPB mRNA]; ERBB4 protein affects the reaction [Lipopolysaccharides results in decreased expression of SFTPC mRNA]; ERBB4 protein affects the reaction [Lipopolysaccharides results in increased expression of SFTPA1 mRNA]; ERBB4 protein affects the reaction [Lipopolysaccharides results in increased expression of SFTPA1 protein]; ERBB4 protein affects the reaction [Lipopolysaccharides results in increased expression of SFTPB protein]; ERBB4 protein affects the reaction [Lipopolysaccharides results in increased expression of SFTPC protein]; ERBB4 protein affects the reaction [Lipopolysaccharides results in increased expression of SFTPD mRNA]PMID:21724861
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