GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sox9 | increases expression | ISO | Sox9 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of SOX9 mRNA; Carbon Tetrachloride results in increased expression of SOX9 protein | PMID:31919559 PMID:32579217 PMID:32996673 | Sox9 | increases response to substance | ISO | Sox9 (Mus musculus) | 6480464 | CTD | SOX9 results in increased susceptibility to Carbon Tetrachloride | PMID:32579217 | Sox9 | multiple interactions | ISO | Sox9 (Mus musculus) | 6480464 | CTD | [Carbon Tetrachloride results in increased expression of SOX9 protein] promotes the reaction [SOX9 protein binds to H19 promoter]; [Ethanol co-treated with Carbon Tetrachloride] results in decreased methylation of SOX9 promoter; [Ethanol co-treated with Carbon Tetrachloride] results in increased expression of SOX9 mRNA; Carbon Tetrachloride promotes the reaction [Ethanol results in decreased expression of SOX9 protein]; GANT 61 inhibits the reaction [Carbon Tetrachloride results in increased expression of SOX9 mRNA]; SOX9 promotes the reaction [Carbon Tetrachloride results in increased expression of H19 mRNA] | PMID:28285099 PMID:32579217 PMID:32996673 | |
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