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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620474
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sox9
Name: SRY-box transcription factor 9
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sox9increases expressionISOSOX9 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of SOX9 proteinPMID:23406266
Sox9multiple interactionsISOSOX9 (Homo sapiens)6480464CTDcobaltiprotoporphyrin inhibits the reaction [IL1B protein inhibits the reaction [Oxygen deficiency results in increased expression of SOX9 protein]]; HMOX1 mutant form inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [IL1B protein inhibits the reaction [Oxygen deficiency results in increased expression of SOX9 protein]]]; IL1B protein inhibits the reaction [Oxygen deficiency results in increased expression of SOX9 protein]PMID:23406266
Sox9multiple interactionsISOSox9 (Mus musculus)6480464CTD[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SOX9 mRNAPMID:30529165
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