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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cx3cl1
Name: C-X3-C motif chemokine ligand 1
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cx3cl1increases expressionISOCX3CL1 (Homo sapiens)6480464CTDGlucose results in increased expression of CX3CL1 mRNA; Glucose results in increased expression of CX3CL1 proteinPMID:19132243 PMID:31655124
Cx3cl1multiple interactionsISOCX3CL1 (Homo sapiens)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]; Clofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Clofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; SB 203580 inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]PMID:19132243
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