GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | affects response to substance | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to 1,2-naphthoquinone; NFE2L2 protein affects the susceptibility to 1,2-naphthoquinone | PMID:19303893 PMID:21384861 | Nfe2l2 | increases activity | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | 1,2-naphthoquinone results in increased activity of NFE2L2 protein | PMID:21384861 PMID:21651925 PMID:25807370 | Nfe2l2 | increases expression | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | 1,2-naphthoquinone results in increased expression of NFE2L2 mRNA | PMID:26862668 | Nfe2l2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to 1,2-naphthoquinone] | PMID:20932822 | |
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