GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | increases activity | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | Cobalt results in increased activity of NFE2L2 promoter | PMID:21643505 | Nfe2l2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | [[tungsten carbide co-treated with Cobalt] results in increased localization of NFE2L2 protein] which results in increased expression of NQO1 mRNA; [tungsten carbide co-treated with Cobalt] results in increased localization of NFE2L2 protein; CAT protein inhibits the reaction [[[tungsten carbide co-treated with Cobalt] results in increased localization of NFE2L2 protein] which results in increased expression of NQO1 mRNA] | PMID:20528745 | | ||||||||||||||||||||||
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