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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:25255
Term: methyl methanesulfonate
Definition: A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol.
Chemical ID: MESH:D008741
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2decreases response to substanceISONfe2l2 (Mus musculus)6480464CTDNFE2L2 protein results in decreased susceptibility to Methyl MethanesulfonatePMID:20932822
Nfe2l2multiple interactionsISONfe2l2 (Mus musculus)6480464CTDNFE2L2 protein affects the reaction [Methyl Methanesulfonate results in increased expression of BTG2 mRNA]; NFE2L2 protein affects the reaction [Methyl Methanesulfonate results in increased expression of SRXN1 mRNA]PMID:22003191
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