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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620349
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:42491
Term: flavone
Definition: The simplest member of the class of flavones that consists of 4H-chromen-4-one bearing a phenyl substituent at position 2.
Chemical ID: MESH:C043562
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2multiple interactionsISOPtgs2 (Mus musculus)6480464CTDflavone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; flavone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]PMID:21341175
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