GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620253
Species: Rattus norvegicus
RGD Object: Gene
Symbol: P2rx3
Name: purinergic receptor P2X, ligand-gated ion channel, 3
Acc ID: CHEBI:22984
Term: calcium atom
Definition: An alkaline earth metal atom that has formula Ca.
CasRN: 7440-70-2
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7353216480464CTD[alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium

Trichloroethylene inhibits the reaction [[alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium]

PMID:12694404
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