GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp12 | increases activity | ISO | Mmp12 (Mus musculus) | 6480464 | CTD | Asbestos, Serpentine results in increased activity of MMP12 protein | PMID:16571779 | Mmp12 | increases expression | ISO | Mmp12 (Mus musculus) | 6480464 | CTD | Asbestos, Serpentine results in increased expression of MMP12 mRNA | PMID:16251409 PMID:16571779 | Mmp12 | multiple interactions | ISO | Mmp12 (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP12 mRNA]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MMP12 mRNA]; rottlerin inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP12 mRNA]; U 0126 inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP12 mRNA] | PMID:16571779 | | ||||||||||||||||||||||
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