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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620195
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp12
Name: matrix metallopeptidase 12
Acc ID: CHEBI:17141
Term: cysteamine
Definition: An amine that consists of an ethane skeleton substituted with a thiol group at C-1 and an amino group at C-2.
Chemical ID: MESH:D003543
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp12increases expressionISOMMP12 (Homo sapiens)6480464CTDCysteamine results in increased expression of MMP12 mRNA; Cysteamine results in increased expression of MMP12 proteinPMID:22532830
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