GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ep300 | affects expression | ISO | EP300 (Homo sapiens) | 6480464 | CTD | Zinc affects the expression of EP300 protein | PMID:16636310 | Ep300 | multiple interactions | ISO | Ep300 (Mus musculus) | 6480464 | CTD | [Zinc promotes the reaction [MTF1 protein binds to EP300 protein]] which results in increased expression of MT1 mRNA; chromium hexavalent ion inhibits the reaction [Zinc promotes the reaction [MTF1 protein binds to EP300 protein]]; EP300 protein affects the reaction [Zinc results in increased expression of MT1 mRNA]; EP300 protein inhibits the reaction [chromium hexavalent ion inhibits the reaction [Zinc results in increased expression of MT1 mRNA]]; Zinc promotes the reaction [MTF1 protein binds to EP300 protein binds to CREBBP protein]; Zinc promotes the reaction [MTF1 protein binds to EP300 protein]; Zinc promotes the reaction [MTF1 protein promotes the reaction [EP300 protein binds to SP1 protein]] | PMID:18458062 PMID:18605988 PMID:21035574 PMID:21467744 | |
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