GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ep300 | decreases expression | ISO | EP300 (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased expression of EP300 protein | PMID:15580028 | Ep300 | multiple interactions | ISO | EP300 (Homo sapiens) | 6480464 | CTD | [trichostatin A co-treated with Quercetin] results in increased expression of EP300 protein; [Vorinostat co-treated with Quercetin] results in increased expression of EP300 protein; EP300 protein affects the reaction [[trichostatin A co-treated with Quercetin] results in increased expression of TNFRSF10B mRNA]; EP300 protein affects the reaction [[trichostatin A co-treated with Quercetin] results in increased expression of TNFRSF10B protein]; EP300 protein affects the reaction [[Vorinostat co-treated with Quercetin] results in increased expression of TNFRSF10B protein]; EP300 protein affects the reaction [Quercetin promotes the reaction [trichostatin A results in increased activity of CASP10 protein]]; EP300 protein affects the reaction [Quercetin promotes the reaction [trichostatin A results in increased activity of CASP3 protein]]; EP300 protein affects the reaction [Quercetin promotes the reaction [Vorinostat results in increased activity of CASP10 protein]]; EP300 protein affects the reaction [Quercetin promotes the reaction [Vorinostat results in increased activity of CASP3 protein]]; Quercetin inhibits the reaction [EP300 protein binds to PTGS2 promoter]; Quercetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]] | PMID:20153296 PMID:21857970 PMID:30958996 | | ||||||||||||||||||||||
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