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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620004 Species: Rattus norvegicus RGD Object: Gene Symbol: Angptl2 Name: angiopoietin-like 2

Acc ID: CHEBI:8228 Term: pioglitazone Definition: A thiazolidenedione that has formula C19H20N2O3S. CasRN: 111025-46-8 Chemical ID: MESH:C060836

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:733949	6480464	CTD	[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANGPTL2 mRNA pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ANGPTL2 mRNA]	PMID:20847119