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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619996
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bche
Name: butyrylcholinesterase
Acc ID: CHEBI:78734
Term: tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate
Definition: A tropane alkaloid that is (1R,5)-8-methyl-8-azabicyclo[3.2.1]octane substituted by a (3-hydroxy-2-phenylpropanoyl)oxy group at position 3.
Chemical ID: MESH:D001285
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bchemultiple interactionsEXP 6480464CTD[Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE proteinPMID:17963125
Bchemultiple interactionsISOBCHE (Homo sapiens)6480464CTD[BCHE protein co-treated with asoxime chloride co-treated with pro-diazepam co-treated with Atropine] results in decreased susceptibility to VXPMID:22981459
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