GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bche | decreases activity | EXP | | 6480464 | CTD | Paraoxon results in decreased activity of BCHE mRNA; Paraoxon results in decreased activity of BCHE protein | PMID:12629810 PMID:19272400 PMID:33497710 PMID:33592259 PMID:4631366 | Bche | affects binding | ISO | BCHE (Homo sapiens) | 6480464 | CTD | Paraoxon binds to BCHE protein; Paraoxon binds to BCHE protein modified form | PMID:18514178 | Bche | decreases activity | ISO | BCHE (Homo sapiens) | 6480464 | CTD | Paraoxon results in decreased activity of BCHE protein | PMID:16213467 PMID:18617161 PMID:20206154 PMID:20227398 PMID:21673941 PMID:24912784 PMID:27693733 PMID:29614332 PMID:33592259 PMID:4631366 | Bche | decreases activity | ISO | Bche (Mus musculus) | 6480464 | CTD | Paraoxon results in decreased activity of BCHE protein | PMID:22209767 PMID:23178380 PMID:27108687 PMID:4631366 | Bche | decreases response to substance | ISO | BCHE (Homo sapiens) | 6480464 | CTD | BCHE protein results in decreased susceptibility to Paraoxon | PMID:31201777 | Bche | decreases response to substance | ISO | Bche (Mus musculus) | 6480464 | CTD | BCHE protein results in decreased susceptibility to Paraoxon | PMID:23178380 | Bche | multiple interactions | ISO | BCHE (Homo sapiens) | 6480464 | CTD | ALB protein results in decreased susceptibility to [Paraoxon results in decreased activity of BCHE protein]; Amodiaquine inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; asoxime chloride inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; BCHE protein inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; BCHE protein inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; Glucosides inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; Metoclopramide inhibits the reaction [Paraoxon binds to and results in decreased activity of BCHE protein]; Obidoxime Chloride inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; Paraoxon binds to and results in decreased activity of BCHE protein; pralidoxime inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; pyridine-4-aldoxime inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; pyridoxaloxime analog inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; Ranitidine inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; Tiapamil Hydrochloride inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; Trimedoxime inhibits the reaction [Paraoxon results in decreased activity of BCHE protein] | PMID:12518340 PMID:15669026 PMID:16193528 PMID:18617161 PMID:20211614 PMID:20227398 PMID:23178380 PMID:27693733 PMID:29614332 | Bche | multiple interactions | ISO | Bche (Mus musculus) | 6480464 | CTD | BCHE protein inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; BCHE protein inhibits the reaction [Paraoxon results in decreased activity of BCHE protein] | PMID:23178380 | |
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