GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | decreases expression | EXP | | 6480464 | CTD | bisindolylmaleimide I results in decreased expression of VEGFA mRNA | PMID:12590138 | Vegfa | multiple interactions | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | bisindolylmaleimide I inhibits the reaction [[Ethanol co-treated with sodium arsenite] results in increased expression of VEGFA mRNA]; bisindolylmaleimide I inhibits the reaction [VEGFA protein affects the localization of RELA protein]; bisindolylmaleimide I inhibits the reaction [VEGFA protein results in increased abundance of phosphatidylbutanol]; bisindolylmaleimide I inhibits the reaction [VEGFA protein results in increased expression of ACE protein]; bisindolylmaleimide I promotes the reaction [VEGFA protein results in increased expression of SOD2 mRNA] | PMID:11158990 PMID:14704231 PMID:15308628 PMID:18210215 | |
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