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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:34288
Term: 2-hydroxyethyl methacrylate
Definition: An enoate ester that is the monomethacryloyl derivative of ethylene glycol.
Chemical ID: MESH:C005044
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfadecreases secretionISOVEGFA (Homo sapiens)6480464CTDhydroxyethyl methacrylate results in decreased secretion of VEGFA proteinPMID:19176594
Vegfamultiple interactionsISOVEGFA (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [hydroxyethyl methacrylate results in decreased secretion of VEGFA protein]; pyrazolanthrone inhibits the reaction [hydroxyethyl methacrylate results in decreased secretion of VEGFA protein]PMID:19176594
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