GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | decreases activity | EXP | | 6480464 | CTD | Capsaicin results in decreased activity of VEGFA | PMID:14744780 | Vegfa | increases expression | EXP | | 6480464 | CTD | Capsaicin results in increased expression of VEGFA protein | PMID:22150557 | Vegfa | multiple interactions | EXP | | 6480464 | CTD | [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of VEGFA protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of VEGFA protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of VEGFA protein] | PMID:22150557 | Vegfa | decreases activity | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Capsaicin results in decreased activity of VEGFA | PMID:14744780 | Vegfa | decreases activity | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Capsaicin results in decreased activity of VEGFA | PMID:14744780 | Vegfa | decreases expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Capsaicin results in decreased expression of VEGFA protein | PMID:17505005 | Vegfa | increases expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Capsaicin results in increased expression of VEGFA mRNA | PMID:12242509 PMID:21310942 | Vegfa | increases secretion | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Capsaicin results in increased secretion of VEGFA protein | PMID:12242509 | |
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