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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:30703
Term: tetrathiomolybdate(2-)
Definition: A molybdenum coordination entity that has formula MoS4.
Chemical ID: MESH:C020809
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfadecreases expressionEXP 6480464CTDtetrathiomolybdate results in decreased expression of VEGFA proteinPMID:16277669
Vegfamultiple interactionsEXP 6480464CTD[Copper deficiency co-treated with tetrathiomolybdate] results in decreased expression of VEGFA mRNA; [Copper deficiency co-treated with tetrathiomolybdate] results in decreased expression of VEGFA proteinPMID:22276220
Vegfadecreases expressionISOVEGFA (Homo sapiens)6480464CTDtetrathiomolybdate results in decreased expression of VEGFA proteinPMID:37290678
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