GENE - CHEMICAL INTERACTIONS REPORT
RGD ID:
619991
Species:
Rattus norvegicus
RGD Object:
Gene
Symbol:
Vegfa
Name:
vascular endothelial growth factor A
Acc ID:
CHEBI:30621
Term:
diarsenic trioxide
Definition:
An arsenic oxide that has formula As4O6.
CasRN:
1327-53-3
Chemical ID:
MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
decreases expression ISO RGD:731072 6480464 CTD arsenic trioxide results in decreased expression of VEGFA mRNA PMID:16928304 PMID:20435036 multiple interactions ISO RGD:731072 6480464 CTD arsenic trioxide inhibits the reaction [VEGFA protein results in increased phosphorylation of MAPK1 protein] PMID:15723287 decreases expression ISO RGD:731072 6480464 CTD arsenic trioxide results in decreased expression of VEGFA PMID:21473291 decreases expression ISO RGD:731072 6480464 CTD arsenic trioxide results in decreased expression of VEGFA mRNA PMID:20435036 PMID:16928304 decreases expression ISO RGD:731072 6480464 CTD arsenic trioxide results in decreased expression of VEGFA protein PMID:20435036 increases expression ISO RGD:731072 6480464 CTD arsenic trioxide results in increased expression of VEGFA PMID:15949266 increases expression ISO RGD:731072 6480464 CTD arsenic trioxide results in increased expression of VEGFA protein PMID:12482858 multiple interactions ISO RGD:731072 6480464 CTD [Genistein co-treated with arsenic trioxide] results in decreased expression of VEGFA protein PMID:21078540 decreases expression ISO RGD:731073 6480464 CTD arsenic trioxide results in decreased expression of VEGFA protein PMID:17007042 increases expression ISO RGD:731073 6480464 CTD arsenic trioxide results in increased expression of VEGFA protein PMID:15888669 increases secretion ISO RGD:731073 6480464 CTD arsenic trioxide results in increased secretion of VEGFA protein PMID:15888669 multiple interactions ISO RGD:731073 6480464 CTD [Genistein co-treated with arsenic trioxide] results in decreased expression of VEGFA protein PMID:21078540 increases expression ISO RGD:731073 6480464 CTD arsenic trioxide results in increased expression of VEGFA mRNA PMID:22488045 multiple interactions ISO RGD:731073 6480464 CTD HMOX1 mRNA affects the reaction [arsenic trioxide results in increased expression of VEGFA mRNA] PMID:22488045 
