GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | affects expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of VEGFA mRNA | PMID:34747641 | Vegfa | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA | PMID:16495355 PMID:24475139 | Vegfa | affects expression | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of VEGFA mRNA | PMID:21570461 | Vegfa | decreases expression | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of VEGFA mRNA | PMID:16120747 PMID:19770486 | Vegfa | increases expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA; Tetrachlorodibenzodioxin results in increased expression of VEGFA protein | PMID:12377990 PMID:17555868 PMID:18388244 PMID:18938131 PMID:19162293 PMID:19182260 PMID:20865247 PMID:28351761 | Vegfa | increases expression | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA; Tetrachlorodibenzodioxin results in increased expression of VEGFA protein | PMID:12167310 PMID:15591033 PMID:18691609 PMID:19063610 PMID:19182260 | Vegfa | multiple interactions | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | 13-hydroxy-10-oxo-11-octadecenoic acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; 3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; [Nifedipine co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in increased expression of VEGFA mRNA; AG 1879 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA protein]; arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; aurapten inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; EGTA acetoxymethyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; methyl arachidonylfluorophosphonate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; zerumbone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA] | PMID:18072750 PMID:18388244 PMID:18938131 PMID:19162293 PMID:19182260 PMID:20865247 | Vegfa | multiple interactions | ISO | Vegfa (Mus musculus) | 6480464 | CTD | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; arachidonyltrifluoromethane promotes the reaction [Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]]; Colforsin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; Vanadates promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA] | PMID:19063610 | | ||||||||||||||||||||||
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