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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:17573
Term: glycyrrhetinate
Definition: A monocarboxylic acid anion that has formula C30H45O4.
Chemical ID: MESH:C119129
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfamultiple interactionsISOVEGFA (Homo sapiens)6480464CTD18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of VEGFA protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]PMID:24613819
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