GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | increases expression | EXP | | 6480464 | CTD | Homocysteine results in increased expression of VEGFA protein | PMID:17485853 | Vegfa | decreases expression | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Homocysteine results in decreased expression of VEGFA mRNA | PMID:20116427 | Vegfa | decreases secretion | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Homocysteine results in decreased secretion of VEGFA protein | PMID:22647887 | Vegfa | multiple interactions | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Amitriptyline inhibits the reaction [Homocysteine results in decreased secretion of VEGFA protein]; CASP1 protein affects the reaction [Homocysteine results in decreased secretion of VEGFA protein]; CYBB protein affects the reaction [Homocysteine results in decreased secretion of VEGFA protein]; diphenyleneiodonium inhibits the reaction [Homocysteine results in decreased secretion of VEGFA protein]; Homocysteine results in decreased expression of and results in decreased secretion of VEGFA protein; PYCARD protein affects the reaction [Homocysteine results in decreased secretion of VEGFA protein] | PMID:20116427 PMID:22647887 PMID:23024785 | |
Go Back to source page | Continue to Ontology report |