GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | multiple interactions | EXP | | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of VEGFA mRNA]; [kaempferol inhibits the reaction [Lipopolysaccharides co-treated with HIF1A protein]] which results in increased expression of VEGFA protein; [kaempferol inhibits the reaction [Lipopolysaccharides co-treated with TNF protein]] which results in increased expression of VEGFA mRNA; [kaempferol inhibits the reaction [Lipopolysaccharides co-treated with TNF protein]] which results in increased expression of VEGFA protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of VEGFA mRNA; [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of VEGFA mRNA; [Lipopolysaccharides co-treated with TNF protein] results in increased expression of VEGFA mRNA; [Lipopolysaccharides co-treated with TNF protein] results in increased expression of VEGFA protein; [MK 2206 inhibits the reaction [Lipopolysaccharides co-treated with TNF protein]] which results in increased expression of VEGFA protein | PMID:16415329 PMID:28844859 PMID:36049518 | Vegfa | increases expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased expression of VEGFA mRNA; Lipopolysaccharides results in increased expression of VEGFA protein; Lipopolysaccharides results in increased expression of VEGFA protein polymorphism | PMID:16385345 PMID:19744167 PMID:22087807 PMID:26918785 PMID:32186776 PMID:34978009 | Vegfa | increases expression | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of VEGFA mRNA; Lipopolysaccharides results in increased expression of VEGFA protein | PMID:12057914 PMID:26962056 PMID:34978009 | Vegfa | increases secretion | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased secretion of VEGFA protein | PMID:24431307 PMID:32800949 | Vegfa | increases secretion | ISO | Vegfa (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased secretion of VEGFA protein | PMID:34978009 | Vegfa | multiple interactions | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]; 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]; bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of VEGFA protein]; bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]; chetomin inhibits the reaction [HIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]]; HIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]; idelalisib inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]; idelalisib inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]; Lipopolysaccharides inhibits the reaction [7-difluoromethyl-5,4'-dimethoxygenistein results in decreased expression of VEGFA mRNA]; Lipopolysaccharides inhibits the reaction [7-difluoromethyl-5,4'-dimethoxygenistein results in decreased expression of VEGFA protein]; Lipopolysaccharides promotes the reaction [Dipyridamole results in increased secretion of VEGFA protein]; Lipopolysaccharides results in increased expression of and results in increased secretion of VEGFA protein; Oxygen deficiency promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]; TLR4 affects the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA] | PMID:19744167 PMID:20067761 PMID:22087807 PMID:26918785 PMID:32186776 PMID:34978009 | Vegfa | multiple interactions | ISO | Vegfa (Mus musculus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]; [Monocrotaline co-treated with Lipopolysaccharides] results in increased secretion of VEGFA protein; bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of VEGFA protein]; Ethylene Chlorohydrin inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]; idelalisib promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]; Lipopolysaccharides results in increased expression of and results in increased secretion of VEGFA protein; Vinyl Chloride metabolite inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA] | PMID:21327618 PMID:26918785 PMID:26962056 PMID:34978009 | |
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