Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Oxygen deficiency results in increased expression of VEGFA mRNA; Oxygen deficiency results in increased expression of VEGFA protein; Oxygen results in increased expression of VEGFA protein
[Oxygen deficiency co-treated with cobaltous chloride] results in increased expression of VEGFA protein; AQP3 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; cobaltous chloride inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; cobaltous chloride inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; cobaltous chloride inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; Dactinomycin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; natakalim inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; norwogonin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; norwogonin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; Oxygen deficiency promotes the reaction [AGT protein results in increased expression of VEGFA protein]; Resveratrol inhibits the reaction [Oxygen results in increased expression of VEGFA protein]; Rutin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Rutin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; Valsartan inhibits the reaction [Oxygen deficiency promotes the reaction [AGT protein results in increased expression of VEGFA protein]]
Oxygen deficiency results in increased expression of VEGFA mRNA; Oxygen deficiency results in increased expression of VEGFA protein; Oxygen results in increased expression of VEGFA protein
(+)-JQ1 compound inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; 3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; 3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; 4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; 4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; 4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; [Apigenin co-treated with Oxygen deficiency] affects the expression of VEGFA mRNA; [Apigenin co-treated with Oxygen deficiency] affects the expression of VEGFA protein; [Curcumin analog co-treated with Sirolimus] inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; [Curcumin analog co-treated with terpestacin] inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; [Curcumin analog co-treated with Vorinostat] inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; [Oxygen deficiency co-treated with eprenetapopt co-treated with Cisplatin] results in increased expression of VEGFA mRNA; [Oxygen deficiency co-treated with eprenetapopt] results in increased expression of VEGFA mRNA; [Polyphenols inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]] which results in decreased expression of VEGFA; [Propolis inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]] which results in decreased expression of VEGFA; [Quinolones co-treated with Oxygen deficiency] results in increased expression of VEGFA mRNA; [Rotenone co-treated with Thenoyltrifluoroacetone] inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in increased expression of VEGFA mRNA; annonacin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; annonacin inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; Apigenin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Apigenin inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; bisphenol A promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; butylbenzyl phthalate promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; CGB3 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Curcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of VEGFA protein]; Cycloheximide promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; CYP2D6 protein inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; CYP3A4 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of VEGFA protein]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Diethylhexyl Phthalate affects the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; dihydrotanshinone I inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; dihydrotanshinone I inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; diphenyleneiodonium inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Edaravone inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Edaravone inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; Estradiol promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; fatostatin affects the reaction [Lipids deficiency inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]]; fisetin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; fisetin inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; fisetin promotes the reaction [Oxygen deficiency results in increased expression of and results in increased localization of VEGFA protein]; galangin promotes the reaction [Oxygen deficiency results in increased expression of and results in increased localization of VEGFA protein]; genipin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; genipin inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; GSK1210151A promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; HIF1A protein alternative form inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; HIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; HIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; KC7F2 compound inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Ketoconazole inhibits the reaction [CYP3A4 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]]; Ketoconazole inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Lipids deficiency inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; Luteolin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Luteolin inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; molibresib inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Mustard Gas inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Mustard Gas inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; myricetin promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; Nitroprusside inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Oxygen deficiency inhibits the reaction [ochratoxin A results in decreased expression of VEGFA protein]; Oxygen deficiency promotes the reaction [BRD4 protein binds to VEGFA promoter]; Oxygen deficiency promotes the reaction [HIF1A protein binds to VEGFA promoter]; Oxygen deficiency promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]; Oxygen deficiency results in increased expression of and results in increased localization of VEGFA protein; Oxygen deficiency results in increased expression of and results in increased secretion of VEGFA protein; Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Polyphenols inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Polyphenols inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; POSTN protein affects the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; POSTN protein affects the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; Propolis inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Propolis inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; Quercetin inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; Quercetin promotes the reaction [Oxygen deficiency results in increased expression of and results in increased localization of VEGFA protein]; Quinolones inhibits the reaction [Mustard Gas inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]]; Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Resveratrol inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; Rotenone inhibits the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Silybin promotes the reaction [Lipids deficiency inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]]; Sirolimus inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; ST6GAL1 protein affects the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; VEGFA protein affects the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of VEGFA protein; AKR1B1 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; ARNT gene mutant form inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Oxygen results in increased expression of VEGFA protein]; CYP1B1 gene mutant form promotes the reaction [Oxygen results in increased secretion of VEGFA protein]; HIF1A protein affects the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; HIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; HMOX1 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; HMOX1 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; Losartan inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; phosphomannopentaose sulfate affects the reaction [Oxygen affects the expression of VEGFA mRNA]; phosphomannopentaose sulfate affects the reaction [Oxygen affects the expression of VEGFA protein]; sorbinil inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]