GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcb1a | decreases activity | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | Disulfiram metabolite results in decreased activity of ABCB1 protein; Disulfiram results in decreased activity of ABCB1 protein | PMID:10841824 PMID:14978246 PMID:16028354 | Abcb1a | multiple interactions | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidopine binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidoprazosin binds to ABCB1 protein] | PMID:14978246 | |
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