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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619930
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb11
Name: ATP binding cassette subfamily B member 11
Acc ID: CHEBI:29013
Term: fusidic acid
Definition: A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum.
Chemical ID: MESH:D005672
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb11decreases activityEXP 6480464CTDFusidic Acid results in decreased activity of ABCB11 proteinPMID:12106615
Abcb11decreases activityISOABCB11 (Homo sapiens)6480464CTDFusidic Acid results in decreased activity of ABCB11 proteinPMID:20829430 PMID:23956101 PMID:24014644
Abcb11multiple interactionsISOABCB11 (Homo sapiens)6480464CTDFusidic Acid inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]PMID:24014644 PMID:27676153
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