GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fas | increases expression | ISO | FAS (Homo sapiens) | 6480464 | CTD | vorinostat results in increased expression of FAS mRNA; vorinostat results in increased expression of FAS protein | PMID:17351739 PMID:18025281 PMID:19737941 PMID:26272509 PMID:27188386 | Fas | multiple interactions | ISO | FAS (Homo sapiens) | 6480464 | CTD | [Bortezomib co-treated with Vorinostat] results in increased expression of FAS protein; [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAS mRNA; [Sorafenib co-treated with Vorinostat] promotes the reaction [CASP8 protein binds to FAS protein binds to FADD protein]; [Sorafenib co-treated with Vorinostat] promotes the reaction [FAS protein binds to CASP8 protein binds to ATG5 protein binds to HSPA5 protein]; [Sorafenib co-treated with Vorinostat] promotes the reaction [FAS protein binds to EIF2AK3 protein]; [Vorinostat co-treated with Sorafenib] affects the localization of FAS protein; [Vorinostat co-treated with Sorafenib] results in increased activity of FAS protein; EIF2AK3 protein promotes the reaction [[Sorafenib co-treated with Vorinostat] promotes the reaction [CASP8 protein binds to ATG5 protein binds to HSPA5 protein binds to FAS protein]]; EIF2AK3 protein promotes the reaction [[Sorafenib co-treated with Vorinostat] promotes the reaction [FAS protein binds to FADD protein binds to CASP8 protein]]; FADD protein promotes the reaction [[Sorafenib co-treated with Vorinostat] promotes the reaction [CASP8 protein binds to ATG5 protein binds to HSPA5 protein binds to FAS protein]]; FAS protein promotes the reaction [[Sorafenib co-treated with Vorinostat] results in decreased expression of ATG5 protein]; FAS protein promotes the reaction [[Sorafenib co-treated with Vorinostat] results in increased phosphorylation of EIF2A protein]; FAS protein promotes the reaction [[Sorafenib co-treated with Vorinostat] results in increased phosphorylation of EIF2AK3 protein]; fumonisin B1 inhibits the reaction [[Sorafenib co-treated with Vorinostat] affects the localization of and results in increased activity of FAS protein]; SMPD1 protein promotes the reaction [[Vorinostat co-treated with Sorafenib] affects the localization of FAS protein]; thermozymocidin inhibits the reaction [[Sorafenib co-treated with Vorinostat] affects the localization of and results in increased activity of FAS protein] | PMID:17351739 PMID:18787411 PMID:27188386 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |