Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fas
Name: Fas cell surface death receptor
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasincreases expressionEXP 6480464CTDAcetylcysteine results in increased expression of FAS mRNAPMID:9227460
Fasmultiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of FAS mRNA]PMID:19477266
Fasmultiple interactionsISOFAS (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of FAS protein]; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of FAS protein]PMID:15382040 PMID:16169029 PMID:19014919 PMID:19720122 PMID:21741372 PMID:28219700
Go Back to source page   Continue to Ontology report