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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619712
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grk1
Name: G protein-coupled receptor kinase 1
Acc ID: CHEBI:74571
Term: iodoacetic acid
Definition: A haloacetic acid that is acetic acid in which one of the hydrogens of the methyl group is replaced by an iodine atom.
Chemical ID: MESH:D019807
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grk1multiple interactionsISOGrk1 (Mus musculus)6480464CTD[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA; Octreotide affects the reaction [SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]]; Octreotide inhibits the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]; SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]PMID:18624922
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