GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp9 | decreases activity | EXP | | 6480464 | CTD | resveratrol results in decreased activity of CASP9 protein | PMID:20861279 | Casp9 | decreases expression | EXP | | 6480464 | CTD | resveratrol results in decreased expression of CASP9 protein modified form | PMID:24040416 | Casp9 | multiple interactions | EXP | | 6480464 | CTD | Resveratrol inhibits the reaction [Fenitrothion results in increased expression of CASP9 mRNA] | PMID:34968465 | Casp9 | decreases activity | ISO | Casp9 (Mus musculus) | 6480464 | CTD | resveratrol results in decreased activity of CASP9 protein | PMID:20940732 | Casp9 | decreases activity | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | resveratrol results in decreased activity of CASP9 protein | PMID:21505870 | Casp9 | increases activity | ISO | Casp9 (Mus musculus) | 6480464 | CTD | Resveratrol results in increased activity of CASP9 protein | PMID:37482209 | Casp9 | increases activity | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | [Resveratrol results in increased activity of CASP8 protein] which results in increased activity of CASP9 protein; Resveratrol analog results in increased activity of CASP9 protein; Resveratrol results in increased activity of CASP9 protein | PMID:11406544 PMID:15827328 PMID:17050787 PMID:18276737 PMID:19423619 PMID:19738051 PMID:20028382 PMID:20484155 PMID:20697895 PMID:20717957 PMID:23954321 PMID:24398169 PMID:32621571 | Casp9 | increases cleavage | ISO | Casp9 (Mus musculus) | 6480464 | CTD | Resveratrol results in increased cleavage of CASP9 protein | PMID:17872969 PMID:22137261 | Casp9 | increases cleavage | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | resveratrol results in increased cleavage of CASP9 protein | PMID:18347188 PMID:18444175 PMID:22923501 PMID:23152798 PMID:24264887 PMID:24299158 PMID:27064016 | Casp9 | increases expression | ISO | Casp9 (Mus musculus) | 6480464 | CTD | resveratrol results in increased expression of CASP9 protein | PMID:25505154 | Casp9 | multiple interactions | ISO | Casp9 (Mus musculus) | 6480464 | CTD | BIRC5 protein affects the reaction [Resveratrol results in increased cleavage of CASP9 protein]; Resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP9 protein]; Resveratrol inhibits the reaction [Isoflurane results in increased activity of CASP9 protein]; Resveratrol results in increased cleavage of and results in increased activity of CASP9 protein; SIRT1 protein affects the reaction [Resveratrol results in increased cleavage of CASP9 protein] | PMID:16322078 PMID:16675471 PMID:22137261 PMID:23922164 | Casp9 | multiple interactions | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of CASP9 protein; [Doxorubicin co-treated with resveratrol] results in increased expression of CASP9 mRNA; [resveratrol co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of CASP9 protein; [resveratrol co-treated with panobinostat] results in increased cleavage of CASP9 protein; [resveratrol co-treated with SB 203580] results in increased activity of CASP9 protein; [resveratrol co-treated with TNFSF10 protein] results in increased activity of CASP9 protein; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [[resveratrol results in increased activity of CASP8 protein] which results in increased activity of CASP9 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [resveratrol results in increased cleavage of CASP9 protein]; resveratrol inhibits the reaction [benzo(e)pyrene results in increased activity of CASP9 protein]; resveratrol inhibits the reaction [MFGE8 protein results in increased activity of CASP9 protein]; resveratrol promotes the reaction [TNFSF10 protein results in increased cleavage of CASP9 protein]; resveratrol promotes the reaction [Tobacco Smoke Pollution results in increased activity of CASP9 protein]; resveratrol results in increased cleavage of and results in increased activity of CASP9 protein; sirtinol inhibits the reaction [resveratrol results in increased activity of CASP9 protein] | PMID:12902349 PMID:14749477 PMID:15763656 PMID:16617056 PMID:17636462 PMID:17823925 PMID:18444175 PMID:19423619 PMID:19959636 PMID:20060927 PMID:20697895 PMID:21505870 PMID:22644961 PMID:22923501 PMID:26969377 | | ||||||||||||||||||||||
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