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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp9
Name: caspase 9
Acc ID: CHEBI:2607
Term: Aloe emodin
Definition: A dihydroxyanthraquinone that is chrysazin carrying a hydroxymethyl group at position 3. It has been isolated from plant species of the genus Aloe.
Chemical ID: MESH:C518327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp9increases activityISOCASP9 (Homo sapiens)6480464CTDaloe emodin results in increased activity of CASP9 proteinPMID:19928967
Casp9increases expressionISOCASP9 (Homo sapiens)6480464CTDaloe emodin results in increased expression of CASP9 protein modified formPMID:19928967
Casp9multiple interactionsISOCASP9 (Homo sapiens)6480464CTD[Fluorouracil co-treated with aloe emodin] affects the expression of CASP9; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP9 protein modified form]PMID:19928967
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