GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp9 | increases cleavage | EXP | | 6480464 | CTD | alpha-Chlorohydrin results in increased cleavage of CASP9 protein | PMID:33651226 | Casp9 | increases expression | EXP | | 6480464 | CTD | alpha-Chlorohydrin results in increased expression of CASP9 mRNA | PMID:30107153 | Casp9 | multiple interactions | EXP | | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP9 protein; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP9 protein]; Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of CASP9 mRNA] | PMID:30107153 PMID:33651226 | Casp9 | decreases expression | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | alpha-Chlorohydrin results in decreased expression of CASP9 mRNA | PMID:27732882 | Casp9 | increases activity | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | alpha-Chlorohydrin results in increased activity of CASP9 protein | PMID:28070108 PMID:35149085 | Casp9 | increases cleavage | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | alpha-Chlorohydrin results in increased cleavage of CASP9 protein | PMID:33651226 | Casp9 | multiple interactions | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | 3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP9 protein]]; 3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of and results in increased activity of CASP9 protein; alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP9 protein; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP9 protein]; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]; Diosgenin promotes the reaction [alpha-Chlorohydrin results in increased expression of CASP9 protein]; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [alpha-Chlorohydrin results in increased activity of CASP9 protein] | PMID:27732882 PMID:33651226 PMID:35149085 | |
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