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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp9
Name: caspase 9
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp9multiple interactionsEXP 6480464CTDSpironolactone inhibits the reaction [Testosterone inhibits the reaction [Sorbitol results in increased activity of CASP9 protein]]; Testosterone inhibits the reaction [Sorbitol results in increased activity of CASP9 protein]PMID:20609311
Casp9decreases expressionISOCasp9 (Mus musculus)6480464CTDTestosterone results in decreased expression of CASP9 proteinPMID:18030663
Casp9decreases expressionISOCASP9 (Homo sapiens)6480464CTDTestosterone results in decreased expression of CASP9 proteinPMID:18030663
Casp9multiple interactionsISOCasp9 (Mus musculus)6480464CTDgingerol inhibits the reaction [Testosterone results in decreased expression of CASP9 protein]PMID:18030663
Casp9multiple interactionsISOCASP9 (Homo sapiens)6480464CTDgingerol inhibits the reaction [Testosterone results in decreased expression of CASP9 protein]PMID:18030663
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