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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3983
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zap70
Name: zeta chain of T cell receptor associated protein kinase 70
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zap70affects expressionISOZap70 (Mus musculus)6480464CTDAcetaminophen affects the expression of ZAP70 mRNAPMID:17562736
Zap70increases expressionISOZAP70 (Homo sapiens)6480464CTDAcetaminophen results in increased expression of ZAP70 mRNAPMID:26690555
Zap70multiple interactionsISOZap70 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of ZAP70 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ZAP70 mRNA]PMID:17585979
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